Six cows were subjected to an intravenous glucose tolerance test (GTT) to evaluate the amount of glucose that is needed to stimulate the release of insulin from pancreas. Four of the cows were in early lactation and two were non-lactating and not pregnant. Series of blood-samples were collected to analyze the concentration of insulin and glucose in the blood. The cows were given lower levels of glucose than have been used in earlier glucose tolerance tests. The levels of glucose given were 7,5 mg/kg BW, 15 mg/kg BW, 30 mg/kg BW and 50 mg/kg BW.

 The aim of the study was auditing medical records examine postoperative blood glucose levels after undergoing CABG surgery. Furthermore the aim was to determine if the ward staff abides the local guidelines frame of reference concerning each ward, regarding Blood glucose measurements and blood glucose levels. The study included 70 patients undergoing CABG surgery at the cardiothoracic surgery, Uppsala University Hospital. The study was conducted by retrospective medical record auditing. Studied factors were postoperative blood glucose levels, number of registered Blood glucose measurements, a current diagnosis of DM and preoperative HbA1c.

The main interest of this study was to investigate whether there is hyperglycemia or hypoglycemia in cows suffering from abomasal displacement and to evaluate the effect of transport on blood glucose. Thirty-six cows with left- or right-sided abomasal displacement were included in the study together with 17 cows with other diseases for comparison. Fifteen cows with abomasal displacement and 7 cows with other diseases were sampled before transport. One third of the cows with abomasal displacement had hyperglycemia when the transport effects were corrected for. Separating this group in left- and right-sided abomasal displacement we found significantly higher blood glucose and insulin levels among cows with right-sided abomasal displacement. An explanation for this difference may be a strong stress response secondary to the right-sided dislocation.

The purpose of this scientific essay is to evaluate if a continuous glucose monitoring system is something that can benefit Swedish animal health care. The study investigates if it is medically possible to use continuous glucose monitoring systems on dogs with an apparatus attached to their bodies. Furthermore, I try to establish whether this is possible in practice and how it could be done. The keywords used were diabetes mellitus, insulin, continuous glucose monitoring, blood glucose monitoring, dog, pet owner and animal nursing care. Furthermore, I wanted to find out if this system could be an alternative to currently established methods to measure the patient?s blood glucose level.

The equine hoof is often manipulated in purpose to achieve a better stride or to reduce the weight on damaged tissue. The living tissue in the hoof can?t store energy as glycogen and is therefore depending on a continuous supply of glucose for its energy production. The purpose of the study was to determine if wedging (i.e. elevating) the heel could influence the hooves glucose and lactate consumption/production. Five standardbred horses were trained to trot on a treadmill without getting physical or mentally tired.

Obese horses with insulin resistance are often also afflicted with laminitis. Horses with these symptoms are given the diagnosis equine metabolic syndrome (EMS). Signs of insulin resistance are excessive accumulation of adipose tissue on the neck, around the withers and on the dorsal area of the hindquarters. Insulin resistance means that the function of insulin is defective and does not stimulate glucose uptake by the cells in the body in the correct way. This will result in an increased insulin release.

The aim of the project was to study the effect of oral administration of glucose and leucin on the resynthesis of muscle glycogen after intense exercise in Standardbred trotters. In a crossover design, 11 Standardbred trotters performed a standardized exercise test on two occasions in order to deplete muscle glycogen. The exercise test comprised a warm up period, 7 repeated bouts of exercise on an uphill 500 m slope, and a recovery period. After the exercise test horses received: 1) a solution of glucose and leucine via a nasogastric tube at 0 minutes and at 240 minutes post exercise and a single bout of glucose at 120 minutes post exercise or 2) water (placebo) at 0, 120 and 240 minutes. Blood samples for measurement of glucose and insulin concentrations were collected at rest, when the horses returned to the stables directly after exercise and throughout the 6 hour recovery phase. During the first recovery hour, samples were collected every 15 minutes and then every 30 minutes over the next 5 hours.

Hematology-instruments that analyze blood cells can at specific cases be followed by manual counting with a hemocytometer. The plastic hemocytometer which has a fixed coverslip and is assigned for disposable use, appears to reduce the problems arising from the use of the traditional glass hemocytometer, for instance coverslip-application difficulty and dust particles. Capillary whole blood sampling may be useful for patients at the emergency department and in addition, a smaller volume of blood is taken compared to venous blood sampling. This study will focus on the platelet- and leukocyte count (PLT and WBC) in venous and capillary blood, in order to compare the plastic- and glass hemocytometers with Sysmex XN-2000 (Sysmex Corporation, Kobe, Japan), and verify if capillary whole blood sampling can be used for the measurement of these hematological parameters. 30 subjects donated both capillary- and venous blood samples and these blood samples were analyzed with glass- and plastic hemocytometers with Sysmex XN-2000 as the reference method.

The purpose of the present study was to explore if blood lactate levels are increased in bitches with pyometra, and if the lactate measurement could be used as a prognostic indicator and to determine outcome. The present study included 16 bitches with pyometra that were admitted to the University Animal Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden. For comparison, a control group consisting of 14 healthy staffowned bitches was also evaluated. In all bitches, a physical examination was performed and blood samples for analysis of haematological and biochemical parameters were obtained. In all bitches with pyometra, surgical ovariohysterectomy was performed and a uterine sample for bacteriological culture and identification was collected.

Background: Peripheral arterial disease (PAD), as a consequence of atherosclerosis in the arteria of the limbs, affects one of ten Swedes older than 65. PAD can develop slowly and silently, and involves an increased risk for cardiac infarction and stroke. Measurement of the patient´s ankle blood pressure and calculation of the ankle-brachial index is an evidence-based method to discover PAD. Objective: To investigate how district nurses and general practitioners perceive this method of examination and experience possible obstacles to why it is not more commonly applied at primary health care centres. Method: Data collected by semi-structured interviews have been processed by qualitative content analysis with a manifest onset.

The bacterium Lactobacillus reuteri, which natural habitat is in the intestine of mammals and birds, uses glycerol as a substrate for production of the antimicrobial compound reuterin. Glycerol has been shown to decrease the number of Escherichia coli in human feces and it is believed to be due to in situ production of reuterin. E. coli belongs to the large family of Enterobacteriaceae, naturally occurring in the intestine, and pathogenic strains of E. coli have been shown to be one of several bacteria causing diarrhoea in calves.

The main objective of this research was to study how increased arterial oxygenation by the use of Pulsed Inhaled Nitric-Oxide (PiNO) influenced the metabolic and cardiovascular parameters on horses undergoing acute abdominal surgery because of colic. The parameters blood lactate, blood glucose, pH and heart rate were evaluated before and during anesthesia and closely after recovery. The study showed that blood lactate concentrations decreased significantly during anaesthesia in horses treated with PiNO compared to non-treated horses. It was also seen that the lactate concentration decreased most in horses with the highest levels before PiNO treatment. Since enhanced oxygen extraction ratio was evident in the PiNO group, improved oxygen delivery to the tissue may be a possible explanation for the improved situation.

Background: Peripheral arterial disease (PAD), as a consequence of atherosclerosis in the arteria of the limbs, affects one of ten Swedes older than 65. PAD can develop slowly and silently, and involves an increased risk for cardiac infarction and stroke. Measurement of the patient´s ankle blood pressure and calculation of the ankle-brachial index is an evidence-based method to discover PAD. Objective: To investigate how district nurses and general practitioners perceive this method of examination and experience possible obstacles to why it is not more commonly applied at primary health care centres. Method: Data collected by semi-structured interviews have been processed by qualitative content analysis with a manifest onset.

AbstractThis report aims, through interviews, observations and literature review to examine what some of the youngest children know about the heart, blood and bloodstream. The sample size was twenty children, half of them are at the age of three and the other half is at the age of six.The interviews showed that children at the age of six had better knowledge than children at the age of three, but one child knew that we have the blood corpuscle in the body. He was also the only one who mentioned the blood corpuscle of all children who participated in the research. Children at the age of three could not see the functional relationship between the blood and heart. One child who was six years told that the air we breathe goes directly in the heart from where the blood is circulating to the rest of the body, together with the food.Keywords: heart, blood, bloodstream, the body.

Background: Prediabetes is caused by relative insulin deficiency and insulin resistance in the body tissue which leads to abnormal blood glucose levels. Prediabetes can over time lead to type 2 diabetes mellitus. To prevent the onset of type 2 diabetes and its complications, it is important to identify early elevated blood glucose levels and thereby prediabetes.Objective: To describe nurses' knowledge and experience regarding the management of patients with prediabetes.Methods: Qualitative descriptive design with individual interviews. Three nurses, three community health nurses and three diabetes nurses were interviewed.Results: The result can be understood from the nurses' experiences of encountering patients with prediabetes. An overarching theme in the analysis was that the nurses are working or aspiring to work preventively.